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Visual Neuroscience group (Richard van Wezel),

Department of Biophysics,

Donders Institute for Brain, Cognition & Behaviour,

Radboud University, Nijmegen, The Netherlands​

Department of Human Genetics/Cognitive Neuroscience

(Nael Kasri, Dirk Schubert),

Radboud University Medical Center,

Nijmegen, The Netherlands​

Affiliations
Contact Me
NEWS

2022-06-22

I have given a presentation at MESA+ 2022 meeting at the University of Twente. It is an interdisciplinary event with many engineers and physicists collaborating with biologists and researchers in medicine. I presented my project ideas on neural competition mechanisms and the applications of the hybrid neuron-computer-interface system (click here). I got a quite few responses afterwards. It was a nice experience.

2022-07-09~13

My project with the neural competition mechanism has been presented at FENS meeting in Paris. The poster was about my dynamic clamp project and it was combined with an in vivo works by my colleagues.

2022-05-04

Happy to see a paper by my colleagues is published now (and I am a humble co-author ;>). https://www-cell-com.ru.idm.oclc.org/cell-reports/fulltext/S2211-1247(22)00557-5… It is about the effect of loss-of-function variants in the schizophrenia risk gene SETD1A on neuronal network activity in human neurons through the cAMP/PKA pathway.

2022-05-01

An abstract of our work on a neural competition mechanism and bistable dynamics has been submitted to ECVP 2022 (European Conference for Vision and Perception). It is titled "Decision making in a dish: fundamental mechanisms of bistable visual information processing in mouse visual cortical brain slices"

2022-03-08

An abstract of my friend, Janine Kerstholt (and I am honoured to be a co-author) has been accepted for a presentation at SOSORT. It is about the treatment of scoliosis with a brace. It is a much less harmful approach than drastic surgeries conventionally practised. Yey to Janine!

2022-02-23

We have submitted our abstract to FENS, Federation of European Neuroscience Societies! It is titled "Processing of bistable visual information in the mouse visual system".

2021-06-03

My paper on a neuro-computational model for border-ownership (edge assignment) is now published in Psychological Review. Our work links the neurophysiological data (from Rudiger von der Heydt's group) to mechanisms of determining the depth order of segmented regions. 

published here

and public summary

https://link.growkudos.com/1kuaqg522v4

preprint version is available here

https://www.biorxiv.org/content/10.1101/2020.05.26.113324v1.article-info

2021-05-08

I am invited to give a talk at Neurotech EU meeting "Neurotech Open Section" on May 13th. I will talk about our novel dynamic clamp approach of neuron-computer interface (NCI) system to investigate dynamics of neural circuit.

2021-02-01

Our new paper about dynamics of bi-stable activity of a pair of neurons, with a neuron-computer interface system, is now published!

https://www.jneurosci.org/content/41/6/1251

 

ABOUT ME

I am a neurophysiologist/vision scientist.

my research includes,

Electrophysiology:

  • neural dynamics of neurons in visual cortex investigated by a neuron-computer interface (NCI)

  • all-optical physiology

  • hippocampal neural circuit

  • non-linear neural responses to oscillatory signals 

  • neural dynamics of hiPSC (induced human pluripotent stem cell) derived cultured network

Visual perception:

  • figure-ground organization and underlying mechanisms

  • illusory and multistable perception

  • neuro-computational modeling for Gestalt-like phenomena such as figure-ground organization, illusion, and multi-stability

  • natural image statistics that reflect global configurations

  • The emergence of non-linear frequency components in EEG frequency tagging paradigm corresponding to Gestalt phenomena

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MY RESEARCH

Why and how do we see things as we do? To answer this question is one of the most challenging tasks in science. One of the most prominent properties of vision is that perception is fundamentally subjective. This is cause our perception is not a passive response of the brain to the retinal inputs. Instead, the brain actively processes signals, organizes them, and establishes the perception. To investigate the neural mechanisms underlying this emergence of perceptual organization, I conduct theoretical research of perceptual organization (neuro-computational models) and, at the same time, run experimental research. I have recently started an electrophysiological project to investigate underlying neural mechanisms of bi-stable perception.

My goal as a scientist is to develop a whole new avenue of research activities that bridge between neural dynamics at single-cell/synaptic level and behavioral properties of the visual system as a whole. For this purpose, I apply the knowledge and skills from my interdisciplinary backgrounds in physics, neuroscience, cognitive science, computer vision and psychophysics.

MY RESEARCH FIELDS and SKILLS

Research Fields

Neuroscience:

neural dynamics; electro-physiology; all-optical physiology; visual cortex; hippocampus; synaptic integration; neurocomputational models;

Vision science:

perceptual organization; figure-ground organization; illusory perception; modal and amodal completion;

Skills

multi-channel patch-clamp recording; in vivo, ex vivo, in vitro (cell culture) neural recordings; iontophoresis;

dynamic clamp system;

optical recording with voltage indicators or calcium indicators; optogenetics;

neurocomputational modelling;

EEG recording with frequency tagging; psychophysics;

Matlab programming; NEURON simulation;

 

TEACHING

Since this September, 2021, I also have a teaching duty as an Education Development Officer of Radboud University. I teach neuroscience at the science faculty. I teach at "Comparative Physiology" course and "Neurons and Synapses".

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multichannel patch clamp recording with dynamic clamp system

underlying bi-stable perception

hippocampal neural circuit

non-linear frequency responses of pyramidal neurons in visual cortex

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NEUROSCIENCE

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VISION SCIENCE

 
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neural mechanisms for perceptual organization

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illusory surface

(theory)

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bi-stable perception

(theory)

bi-stable perception

(experiment)

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illusory surface

(experiment)

border-ownership computation

natural image statistics reflecting global configurations

AWARDS, SEMINARS, INVITED TALKS

I was awarded for Parker B. Francis Foundation fellowship (University of Calgary and University of Kentucky, 1991-1993). I obtained the Fund for Scientific Research Flanders (FWO, Fonds voor Wetenschappelijk Onderzoek) post-doctoral fellowship (2011~2014) and the three years extension of the FWO post-doctoral fellowship (2014~2017). I am awarded European Fellowship from Marie Curie Actions, European Commission (2018~2020).

I have been invited to give presentations at various places, including the St. Louis University (School of Medicine), University of Leuven (Department of Mathematics), University of Leeds (School of Biomedical Sciences), University of Trieste (Department of Psychology), Johns Hopkins University (Bodian Seminar at Mind/Brain Institute), the symposium for the centennial anniversary of Rubin’s figure (University of Copenhagen), Rutgers University (Center of Cognitive Science), the symposium “Amodal completion: Michotte’s legacy and new directions fifty years after ‘Les compléments amodaux’” at European Conference on Visual Perception (ECVP 2014, Belgrade), Netherlands Institute for Neuroscience (NIN, Roelfsema Group), Radboud University (Donders Institute), University of Sussex (laboratory of T. Nowotony, informatics), Tamagawa University (Brain Science Institute, Japan), and Utrecht University (Department of Psychology).

ORGANIZED SYMPOSIUMS

I organized a satellite symposium at VSS (Vision Science Society) 2016 (May) at St. Pete Beach, FL, titled “Are there donuts in vision? Neural computation of global image configuration by a circular receptive field.”, organized with Drs. B. Machilsen (University of Leuven), V. Froyen (University of Leuven), M. Cox (Vanderbilt University) and with invited speakers of R. von der Heyde (Johns Hopkins University), J. Elder (York University) and A. Pasupathy (University of Washington).

I also organized a symposium at ECVP (European Conference on Visual Perception) 2017 (August) in Berlin, titled “Neuro-computational mechanisms to reflect global image structure: from boundary detection to figure-ground organization and shape detection” co-organized with M. Self (Netherlands Insititute of Neuroscience), and with invited speakers of R. von der Heydt (Johns Hopkins University), S. Zucker (Yale University) and A. Pasupathy (University of Washington).

EDUCATIONAL HISTORY

PHD IN PSYCHOLOGY, UNIVERSITY OF LEUVEN, BELGIUM

January 2004 - October 2009

vision science, computer vision

PHD IN MEDICINE, UNIVERSITY OF TSUKUBA, JAPAN

April 1985 - March 1989

neuroscience, electrophysiology

MSC IN MEDICAL SCIENCES, UNIVERSITY OF TSUKUBA, JAPAN

April 1983 - March 1985

neuroscience, electrophysiology

BSC IN PHYSICS, UNIVERSITY OF SAITAMA, JAPAN

April 1977 - March 1981

physics, bio-physics

PAST EXPERIENCE

POST-DOCTORAL FELLOW, BRAIN AND COGNITION, UNIVERSITY OF LEUVEN, BELGIUM

October 2009 - September 2017

vision science, computer vision, electrophysiology

POST-DOCTORAL FELLOW, ESAT-PSI, UNIVERSITY OF LEUVEN, BELGIUM

January 2001 - December 2003

computer vision

POST-DOCTORAL FELLOW, MRC, ANATOMICAL NEUROPHARMACOLOGY UNIT, UNIVERSITY OF OXFORD

April 1998 - December 2000

hippocampus, electrophysiology

POST-DOCTORAL FELLOW, DEPARTMENT OF ANATOMY, ST. LOUIS UNIVERSITY

September 1993 - April 1998

electrophysiology

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PHILOSOPHY

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Research Ethics

CONTACT

Contact me for any questions or just to initiate nice discussions!

Thanks for submitting!